Down Regulation of c-FLIPL Enhance PD-1 Blockade Efficacy in B16 Melanoma
Immune checkpoint blockade of programmed cell death protein 1 (PD-1) had an impressive Stove Hotplate Adaptor long-lasting effect in a portion of advanced-stage melanoma patients, however, this therapy failed to induce responses in several patients; how to increase the objective response rate is very important.Cellular FLICE-inhibitory protein (c-F